Technology

Interstitial cystitis (IC), also called bladder pain syndrome (BPS), is a chronic bladder health issue that strongly affects everyday life of millions of people worldwide. Patients chronically feel pain and pressure in the bladder area and an increasing urge to urinate. The causes for the condition are still unclear and treatment attempts often remain unsatisfactory. …

Neuromodulation: now also a promising candidate for alleviating painful bladders Read More »

Basic research in animal models form an essential milestone on the pathway towards innovative medical treatments. For good reasons, clinical testing in human subjects can only start when the approach has been sufficiently tested and validated in preclinical experiments. Yet, translating a treatment idea from one species to another comes with challenges. Frequent obstacles range …

User Story: Of rats, pig and people Read More »

Functional electrical stimulation of motor nerves or muscles has been used for decades to restore movements in paralyzed patients who suffered a spinal cord injury, for example. The idea is based on the seminal findings by Luigi Galvani in the 18th century. He could induce movements in frog legs when exposing them to electric voltages …

One single nerve – many different movements! Read More »

A central vision of bioelectronic medicine is to find ways to regulate body states through electric interactions with the nervous system rather than through administration of pharmaceuticals. Diabetes is one of the first major targets for this novel approach: Even the most advanced existing pharmaceutical therapies are still error-prone and complicated, often leaving patients with …

Neuronal decoding of decreased blood sugar levels: A first step towards closed-loop bioelectronic diabetes treatment Read More »

One of the major sources for complications in chronic neuromodulation are the wires connecting the different parts of the systems, or even penetrating the skin. They account for frequent device failures due to wire breaks and, especially when penetrating the skin, are a permanent risk of tissue irritations or infections. To overcome these problems, a …

Wireless Neuromodulation with CorTec Cuff Electrodes and novel ‘Electroparticles’ Read More »