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The long and winding road towards specific vagus nerve modulation

The vagus nerve is one of the biggest cranial nerves. It interconnects the brain with almost all internal organs, including the heart, the respiratory tract, the kidney, and the digestive tract. It mediates important reflexes for autonomic functions and modulates a wide range of body functions, making it an attractive target for bioelectronic interventions. On …

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Speak your mind! – Pilot clinical study with severely paralyzed patients

CorTec is part of an international clinical study that will enable severely paralyzed people to communicate again – with the help of an implantable brain-computer interface. It is a vision that has been at the core of CorTec’s DNA since its inception more than 10 years ago by now: Brain-Computer Interfaces (BCI) that enable severely …

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Getting back that feeling.

For a project recently accepted for funding by the NIH, CorTec will supply novel electrodes to help people regain sensation from missing limbs.   Losing a limb not only severely impairs our motor abilities, but also significantly impairs our level of independence. While prostheses can help to regain mobility, one of their biggest shortcomings is …

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A novel wireless research device for chronic pain relief

Electrically stimulating the spinal cord can be an effective therapy for different kinds of treatment-resistant chronic pain. The exact mechanisms through which the stimulation suppresses pain are still not fully understood. In most systems currently used in patients, the electrodes are placed epidurally into the spinal cord canal. There is evidence that the stimulation effects …

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PEDOT coating paired with low frequency alternating currents enables physiological nerve blocks

Delivering electrical currents to nerves can not only serve to stimulate them, by inducing action potentials that are carried along the nerve and finally activate the end organ (e.g., a muscle). Certain stimulation patterns can also suppress nerve activity, leading to an inhibitory effect on the respective end organs. This is of specific interest for …

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A software tool for optimizing peripheral motor stimulation

CorTec’s cuff electrodes have proven extremely helpful as interfaces for electrically interacting with the peripheral nervous system. The range of possible applications is vast. Cuff sizes, shapes and contact arrangements can be tailored to the specific target nerves, and the electrodes can both, stimulate and record. Nerve stimulation is often used for activating muscles, e.g. …

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