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Going through the pain to heal

It has been known for a long time that the vagus nerve can mediate anti-inflammatory responses. These reactions help lower body temperature and keep cytokine production at bay. This is why the vagus nerve is the target of many bioelectronic approaches for treating inflammatory diseases. Interestingly, however, the anti-inflammatory vagus response can also be induced …

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The long and winding road towards specific vagus nerve modulation

The vagus nerve is one of the biggest cranial nerves. It interconnects the brain with almost all internal organs, including the heart, the respiratory tract, the kidney, and the digestive tract. It mediates important reflexes for autonomic functions and modulates a wide range of body functions, making it an attractive target for bioelectronic interventions. On …

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Tetraplegics use their hands again

Tetraplegia is a massively limiting condition, often caused by serious accidents, in which individuals are unable to move their legs or hands. Affected people are completely dependant on caregivers’ help around the clock.  Any assistive device that could help these patients regain some control over their limbs, especially their hands, would be a tremendous achievement. …

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Speak your mind! – Pilot clinical study with severely paralyzed patients

CorTec is part of an international clinical study that will enable severely paralyzed people to communicate again – with the help of an implantable brain-computer interface. It is a vision that has been at the core of CorTec’s DNA since its inception more than 10 years ago by now: Brain-Computer Interfaces (BCI) that enable severely …

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Getting back that feeling.

For a project recently accepted for funding by the NIH, CorTec will supply novel electrodes to help people regain sensation from missing limbs.   Losing a limb not only severely impairs our motor abilities, but also significantly impairs our level of independence. While prostheses can help to regain mobility, one of their biggest shortcomings is …

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CorTec’ Brain Interchange implant system on track for first-in-man study, funded by the NIH

  The proprietary CorTec neuromodulation system “Brain Interchange” was developed for the discovery of novel neurotherapies. With funding by the US-American National Institutes of Health (NIH), and in collaboration with one of the world leaders in the field, Professor Dr. Jeff Ojemann and his team from the University of Washington School of Medicine in Seattle, …

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INTENSE: Dutch neurotechnology network on brain-machine interfaces

With the support of the Netherlands Organisation for Scientific Research, a new research network was established in 2021 that aims to develop new neurotechnological therapies for blindness, deafness, paralysis, and epilepsy. By combining recent knowledge about the brain with new possibilities within neurotechnology, the network’s approach is to establish high-bandwidth, wireless interfaces to the human …

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Looking Inside of Nerves – a New Tool for Bioelectronic Medicine

When electrically stimulating a nerve to modulate a specific body function for treating a disease, it is essential to know exactly what you are doing. Peripheral nerves typically are heterogeneous bundles of fiber groups (fascicles) that can carry a variety of functionally different signals from or to different body parts. To evoke a specific response, …

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